// DeNovoMAGIC™- Hybrid

The ultimate tool for reference genome assembly:

Receive the highest genome assembly quality in a record time. DeNovoMAGIC™ has already been successfully used by hundreds of customers around the globe, building the most challenging reference genomes. Now, with the availability of an accurate long read data our quality got even better.
The newest version of DenovoMAGIC™ employs a real hybrid assembly to benefit the data quality and unique genome coverage of each: short Illumina reads and long PacBio HiFi reads.

Outstanding Results

CROPCANNABISSWEETCANESWEET BASILCITRUS
PLOIDYDiploidTetraploidTetraploidDiploid
ZYGOSITYHeterozygoteHeterozygoteHomozygoteHeterozygote
HAPLOID GENOME SIZE (Gbp)0.83.42.40.4
TOTAL ASSEMBLY SIZE (Gbp)1.67.12.60.63
CONIG N5O (L5O) (Mbp)1.681 (197)1.53 (853)13.1 (57)2.36 (57)
COMPLETE BUSCO GENES98.3%97%97.5%98.2%
SHORT READS APPROXIMATE COVERAGE (PE250X2)x35x35x35x35
LONG READS APPROXIMATE COVERAGE (HiFi)x20x20x20x20

Advantages

DeNovoMAGIC™ – Hybrid provides you with best-in-class genome assembly results

FAST & ACCURATE

DNA-to-Assembly in record delivery time and low error rate – less than 1 in 3Mbp!*

ROBUST

Proven technology – published in peerreviewed papers, and widely used by big corporations

FULL SERVICE

A turn-key solution from DNA to DeNovo genome assembly regardless of complexity and ploidy

HYBRID APPROACH & HIGH CONTIGUITY

Benefiting from complementary attributes of both platforms to reach a gapless assembly 

FULLY PHASED ASSEMBLY

Each contig accurately represents a single allele/ homeolog/ paralog sequence. The output represents all unique sequences present

CHROMOSOME SCALE

Ordering to pseudo chromosomes using an existing reference

*Avni, R. et al. 2017. Wild emmer genome architecture and diversity elucidate wheat evolution and domestication. Science, 357(6346)

How it Works

 An extensive yet simple tool for analyzing, storing and mining unlimited volumes of genomic data

DeNovoMAGIC delivers the most progressive and novel ability. The  only method to truly discover the entire content of the genome!

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Frequently Asked Questions

What is the meaning of a ‘phased assembly’?

For every diverged homolog or homeolog sequence (originating from heterozygosity or polyploidy respectively) there will be two different scaffolds in the delivered assembly, correctly capturing the actual genome sequence.

What is the delivery time?

Results can be delivered in 4 months or less from sequence data availability

Can I get to chromosome-level in my assembly?

Yes, when provided with an existing physical or genetic map, we can order scaffolds to pseudo-molecules. If no such map is available, we can generate one for you. See our TraitMAGIC offer for more details on the creation of a genetic map.