// TraitMAGICTM

Pave the way to smarter breeding by unraveling the causation elements in your population genomics

Quickly discover the phenotype-genotype correlations in any organism with NRGene’s complete trait-mapping package.
We’ll generate a highly-accurate genetic map which is utilized to order the pseudo-chromosomes and allows for complete phasing in a segregating population. Our special skim-sequencing derived analysis brings a new level of detail to genomic analysis and unlocks the secrets of your population-genomics.

TraitMAGIC – Explained

Outstanding Results

REAL CASE STUDY 1 (HOMOZYGOTE):

241 significant loci affecting 129 fruit quality traits were identified by converting over 58,000 markers to 3,663 haplotype bins in a melon RIL population*

* Galpaz, N. et al. 2018. Deciphering Genetic Factors that Determine Melon Fruit‐Quality Traits Using RNA‐Seq‐Based High‐Resolution QTL and eQTL Mapping. The Plant Journal.

REAL CASE STUDY 2 (HETEROZYGOTE):

A phased haplotype approach (TraitMAGIC) was found superior to a consensus marker-based approach even when applied to <25% of a heterozygote F1 population.

METHOD# OF PROGENY ANALYZED# OF LOCI IDENTIFIEDPREDICTION ACCURACY*
NRGENE200>870%
ALTERNATE>80010%

* percentage of progeny whose phenotype can be predicted with high accuracy based on the results.

Advantages

Translate the most complex trait genetics to a simple and accurate prediction

Highly accurate

We generate high-density marker maps for producing extremely accurate trait mapping, even in the most complex genomes

A unique phased solution for heterozygotes

Proven ability to identify, and correctly phase and map sequences even in complex heterozygote cases

Turn-key solution

We provide sequencing, marker discovery, genotyping, and trait mapping.Send us DNA and phenotype data and we will do the rest

How it Works

AN EXTENSIVE YET SIMPLE TOOL FOR ANALYZING, STORING AND MINING UNLIMITED VOLUMES OF GENOMIC DATA

Related Videos

Play Video

“NRGene’s webinar  – Finding the needles in your haystack”

May 2019

Play Video

“Ultra-High Resolution QTL Mapping of Fruit Quality Traits in Melon”

Speaker: Dr. Nurit Katzir
Agricultural Research Organization,
Newe Ya’ar Research Center

Frequently Asked Questions

What does ‘phased Genetic map’ mean?

It means that the two parental contributions of a segregating population are completely separated and parental meiotic components for each progeny are fully reconstructed.

How does the phasing improve trait mapping results?

Two unique features provide superior mapping results: 1. Phasing: it could be that each parent is heterozygous for different QTLs and only a phased map enables the detection of these. 2. Haplotype bins are used and not single markers, allowing for powerful statistics at the maximal true resolution (improving both specificity and sensitivity compared with using single markers).

May I see a use case for which this method has been applied?
This method has been applied by different commercial and academic customers for various organisms. As we respect our customers data privacy we can refer to this published paper: https://onlinelibrary.wiley.com/doi/abs/10.1111/tpj.13838